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BPC-157 (Body Protection Compound-157) is a synthetic 15-amino acid peptide derived from a protective protein found in human gastric juice . Research suggests it supports tissue repair, reduces inflammation, and promotes healing in muscles, tendons, ligaments, and the gastrointestinal tract through enhanced angiogenesis and growth factor modulation . Available in 5mg and 10mg lyophilized (freeze-dried) powder vials for research purposes.
BPC-157 is a stable pentadecapeptide consisting of 15 amino acids with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val . It is a synthetic analog derived from a partial sequence of a protein naturally found in human gastric juice, where it functions to promote mucosal integrity and homeostasis .
Key Specifications:
Molecular Formula: C₆₂H₉₈N₁₆O₂₂
Molecular Weight: ~1419.5 Da
CAS Number: 137525-51-0
Purity: >97% (typical for research-grade material)
Form: Sterile filtered white lyophilized powder
Preclinical research indicates BPC-157 promotes healing through several pathways :
Angiogenesis – Stimulates new blood vessel formation via VEGFR2-NO signaling, improving blood supply to injured tissues
Growth Hormone Receptor Expression – Enhances GHR expression in fibroblasts, augmenting anabolic healing responses
Anti-inflammatory Effects – Reduces inflammatory cytokines at injury sites
Fibroblast Proliferation & Collagen Synthesis – Accelerates tendon, ligament, and muscle repair through FAK-paxillin signaling pathways
Preclinical studies have explored BPC-157 for :
Musculoskeletal Injuries – Tendon ruptures, ligament tears, muscle injuries, and fractures
Gastrointestinal Conditions – IBD, GI ulcers, NSAID-induced injury, and anastomotic healing
Tissue Protection – Cytoprotective effects in liver, pancreas, and nervous system tissues
| Vial Size | Description |
|---|---|
| 5mg | Standard research dose; suitable for short-term protocols or lower-concentration reconstitution |
| 10mg | Larger quantity for extended research protocols or higher-concentration preparations |
Reconstitution :
Recommended diluent: Bacteriostatic water or sterile 0.9% saline
Add diluent gently against the vial wall; swirl—do not shake
Common concentration example: 5mg vial + 2mL diluent = 2.5mg/mL (~2500 μg/mL)
Storage :
Lyophilized powder: Store below -18°C (freezer), desiccated; stable for up to 2-3 years
Reconstituted solution: Store at 4°C (refrigerator); use within 2-7 days; for longer storage, freeze at -18°C (avoid freeze-thaw cycles)
Research Use Only – Not approved for human therapeutic use; lacks FDA approval
No Clinical Safety Data – While preclinical studies report no adverse effects, human safety data is unavailable
Regulatory Status – Placed in FDA Category 2 (cannot be compounded by commercial pharmacies); banned by WADA
Short Half-Life – Metabolized in the liver with a half-life of <30 minutes; cleared renally
| Weight | 5mg, 10mg |
|---|
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